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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T72046 | PF-17 | Others | |
PF-17 can be used as a PUF60 inhibitor for the treatment of ovarian cancer. | |||
T64337 | PF-04745637 | PF4745637,PF 4745637,PF 04745637,PF-4745637 | TRP/TRPV Channel |
PF-04745637 is a potent and selective TRPA1 antagonist with an IC50 of 17 nM[1]. | |||
TQ0010 | Brepocitinib | PF-06700841 | Tyrosine Kinases , JAK |
Brepocitinib (PF-06700841) is a potent dual JAK1/TYK2 inhibitor (IC50s: 17 nM/23 nM). Brepocitinib also inhibits JAK2/3 (IC50s: 77 nM/6.49 μM). | |||
T13237L | Ropsacitinib | Tyk2-IN-8,PF-06826647 | Tyrosine Kinases |
Ropsacitinib (PF-06826647) is a selective TYK2 inhibitor, which binds to TYK2 catalytically active JH1 domain (IC50: 17 nM). | |||
T12427 | Brepocitinib P-Tosylate | PF-06700841 P-Tosylate | JAK |
Brepocitinib P-Tosylate (PF-06700841 P-Tosylate) is a potent dual inhibitor of Janus kinase 1 (JAK1) and TYK2 (IC50s of 17 nM and 23 nM, respectively). | |||
T21548 | PF-4981517 | CYP3cide | P450 |
PF-4981517 (CYP3cide) is a efficient, specific and time-dependent inhibitor of cytochrome P4503A4 (CYP3A4). The IC 50 values for CYP3A activity are 0.03 μM,17 μM, and 71 μM for CYP3A4, CYP3A5, and CYP3A7, respectively. P... | |||
T3430 | PF-4136309 | INCB8761,PF 4136309 | CCR |
PF-4136309 (INCB8761) is a specific, effective, and orally bioavailable CCR2 antagonist. | |||
T70751 | PF-719 free base | ||
PF-719 is a potent, selective Pyk2 inhibitor with IC50 of 17 nM. |